奥拉西坦与血栓通注射液联合治疗脑梗死的疗效分析

The Effect Analysis of the Combination Treatment of Oxiracetam and Xueshuantong Injection for Cerebral Infarction

目的探讨奥拉西坦与血栓通注射液联合治疗脑梗死的临床疗效。方法 80例脑梗死患者随机分组各40例,两组均使用血栓通注射液400mg加入生理盐水250ml静脉滴注,每日1次,疗程4周,阿司匹林100mg,1次/d,口服。治疗组在对照组基础上给予奥拉西坦注射液4g加入生理盐水250ml静脉滴注,1次/d,疗程4周。治疗前后分别进行神经功能缺损评分。结果治疗后神经功能缺损评分均明显低于治疗前,差异有统计学意义(P<0.05);治疗后神经功能缺损评分,治疗组评分低于对照组,差异有统计学意义(χ2=3.69,P<0.05)。不良反应无差异(χ2=0.74,P>0.05)。结论血栓通与奥拉西坦注射液联合治疗脑梗死疗效显著,能有效改善患者的病情和生活质量,值得临床进一步推广应用。

Objective To investigate the clinical effect of oxiracetam and xueshuantong injection in treating cerebral infarction. Methods 80 patients with cerebral infarction were randomly divided into two groups,each group had 40 patients,both groups were given the intravenous infusion of xueshuantong injection 400 mg and 250 ml normal saline,once a day for 4 weeks,aspirin 100 mg,one time /d,oral. Based on the control group,the treatment group were given the intravenous infusion of oxiracetam injection 4 g and 250 ml normal saline,once a day for 4 weeks. The neurologic deficit scores were carried out before and after treatment. Results After treatment the neurologic deficit scores were significantly lower than those before treatment,the difference was statistically significant（P 0.05）;the neurologic deficit scores of the treatment group after treatment were lower than those of the control group,the difference was statistically significant（χ2 = 3.69,P 0.05） . There was no difference in adverse events（χ2 = 0.74,P 0.05） . Conclusion The effect of oxiracetam and xueshuantong injection in treating cerebral infarction is obvious,which can effectively improve the patients＇ condition and quality of life,so it is worthy of further clinical application.