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孕妇外周血中胎儿有核红细胞分离和应用研究 被引量:3

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摘要 无创性产前实验诊断是指利用非侵入性方法获取胎儿细胞或核酸等物质,用于诊断胎儿是否携带遗传性疾病和先天性疾病。与传统羊水穿刺、绒毛膜取样等方法相比,该类方法最大的优势是不会引起孕妇感染、胎儿流产等并发症,因此成为当前研究的热点。现就从孕妇外周血中分离胎儿有核红细胞(fetal nucleated red blood cells,FNRBC)进行产前诊断研究的现状综述如下。
出处 《国际检验医学杂志》 CAS 2011年第6期669-670,共2页 International Journal of Laboratory Medicine
关键词 孕妇 胎儿 研究
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参考文献10

  • 1Huang R,Barber TA,Schmidt MA,et al.A microfluidics approach for the isolation of nucleated red blood cells(NRBCs)from the peripheral blood of pregnant women[J].Prenat Diagn,2008,28(28):892-899.
  • 2Daniel L,Ponnusamy S,Aniza M,et al.Separation of model mixtures of epsilon-globin positive fetal nucleated red blood cells and anucleate erythrocytes using a microfluidic device[J].Journal of Chromatography A,2010,64(71):1862-1866.
  • 3D′Souza E,Sawant PM,Nadkarni AH,et al.Evaluation of the use of monoclonal antibodies and nested PCR for noninvasive prenatal diagnosis of hemoglobinopathies in India[J].Am J Clin Pathol,2008,130(86):202-209.
  • 4Kwon KH,Jeon YJ,Hwang HS,et al.A high yield of fetal nucleated red blood cells isolated using optimal osmolality and a double-density gradient system[J].Prenat Diagn,2007,27(19):1245-1250.
  • 5Babochkina T,Mergenthaler S,Lapaire O,et al.Evaluation of a soybean lectin-based method for the enrichment of erythroblasts[J].J Histochem Cytochem,2005,53(22):329-330.
  • 6Nagy GR,Bán Z,Sipos F,et al.Isolation of epsilon-haemoglobin-chain positive fetal cells with micromanipulation for prenatal diagnosis[J].Prenat Diagn,2005,25(14):398-402.
  • 7Krabchi K,Gadji M,Yan J,et al.Dual-color PRINS for in situ detection of fetal cells in maternal blood[J].Methods Mol Biol,2006,334(14):141-149.
  • 8Simone N,Lai M,Rumi C,et al.Non-invasive detection of fetal rhesus D status:a comparison between polymerase chain reaction and flow cytometry[J].Fetal Diagn Ther,2006,21(12):404-409.
  • 9Mavrou A,Kouvidi E,Antsaklis A,et al.Identification of nucleated red blood cells in maternal circulation:a second step in screening for fetal aneuploidies and pregnancy complications[J].Prenat Diagn,2007,27(8):150-153.
  • 10Aali BS,Malekpour R,Sedig F,et al.Comparison of maternal and cord blood nucleated red blood cell count between pre-eclamptic and healthy women[J].J Obstet Gynaecol Res,2007,33(11):274-278.

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