丙型病毒性肝炎患者流行及治疗现状调查

Epidemiologic and therapeutic status study of patients with hepatitis C

目的探讨丙型病毒性肝炎患者的感染途径、从感染到发现病情所需时间、从发现病情到治疗所需时问。方法对2004年3月至2010年7月到广州市第八人民医院就诊的216例慢性丙型病毒性肝炎患者的感染途径、发现病情年限和治疗年限进行回顾性分析。结果72．22％的患者患有输血后丙肝（PTHC），27．78％的患者患有散发性丙肝（SHC）。32．61％的患者感染丙肝病毒15～20年后才发现病情，3．26％的患者20年以上才发现病情，33．80％的患者发现病情5年以上给予抗病毒治疗，17．13％的患者发现病情1O～15年后才给予治疗。结论大多数患者通过输血或血制品感染上丙肝，大多数患者感染丙肝病毒15年以上才发现病情，有将近一半的患者发现病情5年以上进行治疗，相当一部分发现病情10余年后才进行治疗。

Objective To investigate the different infective mode, the time from be infectived to be diagnosed and the time from be diagnosed to be treated of patients with hepatitis C. Methods The different infective mode, the time from be infectived to be diagnosed and the time from be diagnosed to he treated of 216 patients with hepatitis C from march 2004 to march 2009 were retrospectively analyzed. Results 72.22 percents patients suffered from post transfusion hepatitis C （PTHC） and 27.78 percents patients suffered from sporadic hepatitisC （SHC）. 32.61 percents patients were diagnosed after be infectived 15-20 years later. 3.26 percents patients were diagnosed after be infectived more than 20 years later. 33.80 percents patients were treated after be diagnosed more than 5 years later. 17. 13 percents patients were treated after be diagnosed 10-15 years later. Conclusion Most patients were infeetived with hepatitis C by transfusing blood or blood products. Most patients were diagnosed after be infectived more than 15 years later. Almost half of patients were treated after be diagnosed more than 5 years later, and a significant portion of percents patients were treated after be diagnosed more than 10 years later.