摘要
目的:探讨脑肿瘤瘤周水肿的MSCT灌注特点及其在脑肿瘤诊断与鉴别诊断中的临床应用价值。方法:对58例脑肿瘤(胶质瘤20例,转移瘤17例,脑膜瘤21例)患者进行常规CT扫描和CT灌注扫描。瘤周水肿区分为近侧和远侧两个部分,对照分析近侧、远侧水肿区以及正常脑组织的CT灌注参数的差异及相关性。结果:高级别胶质瘤、恶性脑膜瘤的近侧瘤周水肿区的CBF、CBV、PS值高于低级别胶质瘤、转移瘤、脑膜瘤的近侧瘤周水肿区(P<0.05);各种脑肿瘤近侧瘤周水肿区的CBF、CBV值明显低于对侧相应部位脑白质的CBF、CBV值,其间差异有统计学意义(P<0.05)。高级别胶质瘤、恶性脑膜瘤近侧瘤周水肿区的PS值高于对侧相应部位脑白质的PS值,其间差异有统计学意义(P<0.05)。低级别胶质瘤、转移瘤、良性脑膜瘤近侧瘤周水肿区与对侧相应部位脑白质的PS值比较差异无统计学意义(P>0.05)。结论:近侧瘤周水肿区的灌注参数有助于准确评价脑肿瘤瘤周水肿区的血流动力学改变及良恶性脑肿瘤的鉴别。
Objective：To evaluate the potential of CTP in diagnosing brain tumors and defining the tumor boundary by analysing the parameters obtained from peritumoral edema.Methods：Fifty-eight patients with brain tumors underwent routine and perfusion CT imaging.The peritumoral low-attenuation region was divided into two regions.Comparisons of CBF,CBV,and PS were done among distant peritumoral region,immediate peritumoral region,and contrallateral normal white matter.Results：CBF,CBV,PS in immediate peritumoral edema of high-grade gliomas and malignant meningiomas were significantly higher than those of low-grade gliomas,metastases and benign meningiomas（P〈0.05）.PS in immediate peritumoral edema of high-grade gliomas and malignant meningioma were higher than that of contrallateral normal white matter（P〈0.05）.PS in immediate peritumoral edema of low-grade gliomas,metastases and benign meningiomas were not different from that of contrallateral normal white matter（P〉0.05）.Conclusion：Hemodynamic changes in peritumoral brain edema could be accurately evaluated by CT perfusion examination.
出处
《放射学实践》
北大核心
2011年第5期483-487,共5页
Radiologic Practice
