超声造影对良恶性肝脏局灶性病变的鉴别诊断价值

Value of contrast-enhanced ultrasound in the differential diagnosis of focal liver lesions

目的:探讨超声造影(CEUS)对良恶性肝脏局灶性病变(FLL)的鉴别诊断价值。方法:应用超声造影反向脉冲谐波显像(PIH)技术实时观察52例(57个病灶)FLL血流灌注增强方式,并通过TIC定量参数对FLL血流灌注进行定量评估。结果:37个恶性病灶与20个良性病灶比较,各参数(始增时间、达峰时间、峰值强度、始消时间、消退后强度、峰值强度与延迟期强度差值)差异均有统计学意义(P<0.05)。当将病灶峰值强度与消退后的差值为7dB作为鉴别诊断良、恶性病灶的区分点时,诊断良、恶性病变的符合率分别为91%和90%。结论:肝脏局灶性病灶峰值强度和消退后强度的差值对于FLL的良恶性鉴别诊断有重要价值。

Objective：To investigate the value of contrast-enhanced ultrasound（CEUS） in the differential diagnosis of focal liver lesions（FLL）.Methods：The perfusion patterns of 52 patients with 57 lesions were observed with the pulse inversion harmonic（PIH） imaging technique.The perfusion quantity of FLL was analyzed according to the acoustic quantified parameters on the TIC.Results：37 malignant tumors and 20 benign lesions were compared.The differences of the parameters（beginning enhancing time、peak time、peak intensity、beginning diminish time、delay intensity、the D-value of the peak and the delayed phase intensity） all had statistical significance（P〈0.05）.When the D-value of the peak and the delay intensity of the lesions was 7dB,the correspondence rate in diagnosing the benign lesions and the malignant tumors reached 91% and 90%.Conclusion：The D-value of the peak and the delay intensity in contrast-enhanced ultrasound have Important value in differentiating the benign and the malignant lesions of liver.