无糖尿病史急性心肌梗死患者入院早期动态血糖谱

A continuous glycemic observation during early phase of acute myocardial infarction in patients without known diabetes mellitus

对连续111例急性心肌梗死患者采用动态血糖监测方法观察早期血糖波动情况，根据血糖代谢紊乱程度依次分为血糖正常组（30例）、一过性血糖升高组（36例）和持续性血糖升高组（45例）。与其他2组比较，持续性血糖升高组患者平均血糖、血糖水平标准差、最大血糖波动幅度、平均血糖波动幅度和日间血糖平均绝对差显著升高（均P〈0．01），男性较少（P〈0．05），陈旧性心梗、高血压更多（P〈0．05），谷草转氨酶、肌酸磷酸激酶、肌酸磷酸激酶同工酶、总胆固醇、甘油三酯、低密度脂蛋白胆固醇、HbA1c、C反应蛋白更高（均P〈0．01）。

[Summary] One hundred and eleven patients with acute myocardial infarction and without known diabetes mellitus who underwent continuous glucose monitoring were divided into normoglycemia （ n=30 ） , transient hyperglycemia（ n = 36 ） , and persistent hyperglycemia（ n = 45 ） groups. Compared with other two groups, higher mean blood glucose, standard deviation of blood glucose, largest amplitude of glycemic excursions, mean amplitude of glycemic excursions, and absolute mean of daily differences were observed in the patients with persistent hyperglycemia group（ all P〈0.01 ） , who were more likely to be female with the history of hypertension and old myocardial infarction （ all P〈0.05 ）. It was shown that the levels of aspartate aminotransferase, creatine phosphokinase （ CK）, CK-MB, total cholesterol, triglyceride, low-density lipoprotein cholesterol, HbA1c, and C reactive protein levels were higher in these patients （P〈0.01）.