多发性硬化的MRI诊断

MRI Diagnosis of Multiple Sclerosis

目的：提高对多发性硬化（MS）MRI特征的认识。材料与方法：对22例MS患者行脑和／或脊髓MRI检查，对病变的分布、形态及病变的强化进行评价。结果：脑内病变位于测脑室周围、半卵圆中心及脑干、室旁病变其长轴多与侧脑室垂直；脊髓病变多位于预髓及上段胸髓，呈长条状。病变急性期及活动期强化，稳定期或斑痕期不强化。结论：MRI可显示MS的特征性表现，增强扫描可提高MRI对MS早期诊断的特异性，并能对MS的病理生理特点进行时间顺序学方面的观察。

Purpose: To get a better understanding of the characteristic MR appearance of MS lesions. Materials and Methods: 22 MS patients underwent MR examination. The locations, shapes and appearances of the lesions before and after injection of Gd - DTPA were analysed. Results: The cerebral lesions were mainly located arround the lateral ventricles, in the centrum semivales and the brain stem, the long axes of the parventricular lesions were perpendicular to the lateral ventricles; The spinal lesion were mainly located in the cervical and upper thoracic cord, shaped as long strips. The actue and active lesions can be enhanced while the stable and scarred lesions can not. Conclusion: MR is capable of demonstrating the characteristic appearance of MS lesions, thus enables us early diagnosis of MS. It also serial visualization of the lesions according to their pathophysiologic charateristics.