瑞芬太尼靶控输注复合丙泊酚用于老年无痛胃镜患者的临床观察

The clinical observation of Remifentanil target- controlled infusion combined with Propofol used in painless gastroscopy of elderly patients

目的观察瑞芬太尼靶控输注复合丙泊酚用于老年无痛胃镜检查的安全性及有效性。方法接受无痛胃镜检查的60例老年患者(ASAⅠ～Ⅱ级)随机分为2组:瑞芬太尼靶控输注复合丙泊酚组(RP组)和丙泊酚组(P组),每组各30例。记录术前(T_0)、给药后1 min(T_1)、术中(T_2)和苏醒时(T_3)时点的SBP、DBP、HP、SpO_2;诱导时间、检查时间、苏醒时间、清醒时间、丙泊酚用量及不良反应。结果 T_1、T_2时点P组SBP、DBP、HR均低于RP组(P<0.05),RP组苏醒时间、清醒时间明显短于P组(P<0 05),RP组丙泊酚用量明显少于P组(P<0.05)。结论瑞芬太尼靶控输注复合丙泊酚可为老年无痛胃镜提供安全可靠的麻醉。

Objective To observe the security and validity of Remifentanil target - controlled infusion combined with Propofol used in painless gastroscopy of elderly patients.Methods Sixty ASAⅠ～Ⅱelderly patients undergoing painless gastroscopy were randomly divided into 2 groups：Remifentanil target- controlled infusion combined with Propofol group（group RP） and Propofol group（group P） with 30 cases in each group.The data of SBP,DBP,HR,SpO_2 preoperative （T_0）,after administration 1 min（T_1）,during surgery（T_2） and wake-up time（T_3） were recorded,while the time of induction,inspection,recovery,being awake,the dose of Propofol and adverse reactions were recorded.Results The SBP,DBP and HR at T_1 and T_2 in group P were lower than in group RP（P0.05）.The time of recovery and being awake in group RP were shorter than in group P（P0.05）,the dose of Propofol in group RP was less than in group P（P0. 05）.Conclusion It is a safe and reliable anesthesia that Remifentanil target - controlled infusion combined with Propofol are used in painless gastroscopy of elderly patients.