银杏叶提取物联合高压氧治疗急性脑梗死的临床观察与评价

Clinical observation and evaluation on treatment for acute cerebral infarction treated with ginkgo leaf extract combined with hyperbaric oxygen

目的评价银杏叶提取物舒血宁联合高压氧对急性脑梗死患者的临床疗效。方法将急性脑梗死患者230例随机分为A组舒血宁联合高压氧治疗100例,B组舒血宁与基础治疗80例,C组高压氧与基础治疗50例,疗程均为15 d×2。观察3组治疗前后的神经功能缺损评分,血液流变学变化及临床疗效,比较评价。结果 A组、B组、C组临床有效率分别为89.0%(89/100)、80.0%(64/80)和72.0%(36/50);3组治疗后神经功能缺损评分和血液流变学指标均有不同程度降低,A组最好,B组次之,C组降低较少,舒血宁与高压氧联用有协同作用。结论银杏叶提取物舒血宁联合高压氧治疗急性脑梗死的疗效显著,值得推广。

Objective To evaluate the clinical treatment effect for acute cerebral infarction by Shu Xue Ning and the extract of ginkgo leaf combined with hyperbaric oxygen.Methods 230 cases of acute cerebral infarction were divided randomly into Group A（n=100） treated with Shu Xue Ning combined with hyperbaric oxygen,Group B（n=80） treated with Shu Xue Ning and conventional treatment and Group C（n=50） treated with hyperbaric oxygen and conventional treatment.The treatment course of each group was 15 days,two courses.The neural function defect scale,blood rheology change and clinical treatment effect of the three groups before and after treatment were observed,compared and evaluated.Results The effective rate of Group A,B and C was 89.0%（89/100）,80.0%（64/80） and 72.0%（36/50） respectively.The neural defect scale and blood rheology parameters were lowered at certain degree,Group A was the best,Group B was the better and Group C was the least.The combination of Shu Xue Ning and hyperbaric oxygen had synergic action.Conclusion The combination of ginkgo leaf extract and Shu Xue Ning with hyperbaric oxygen has obvious treatment effect for acute cerebral infarction so it can be widely used.