孟鲁司特钠治疗儿童非典型哮喘32例临床疗效观察

The clinical observation of Montelukast in the treatment of 32 cases with atypical asthma

目的探讨孟鲁司特钠治疗儿童非典型哮喘的临床疗效。方法 32例非典型哮喘患儿行常规实验室检查后,服用孟鲁司特钠咀嚼片,每晚服1次,<2岁的患儿2.5 mg/次;3岁～4岁的患儿,3.5 mg/次;5岁～14岁的患儿,5 mg/次。结果 12例治疗7 d后咳嗽消失;10例用药14 d症状消失;4例持续用药45 d咳嗽消失;6例患儿加入糖皮质激素吸入第4天其症状改善,6 d后肺部痰鸣音和水泡音消失。结论孟鲁司特钠对呈肺炎表现的非典型哮喘具有良好的防治作用。

Objective To explore the clinical effect of Montelukast sodium in the treatment of atypical asthma.Methods Thirty-two cases of atypical asthma received routine laboratory examination and took Montelukast sodium chewable tablets once per night with the following instructions： 2-year-old children 2.5 mg/times;3～4 years old,3.5 mg/times;5～14-year-old,5 mg/times.Results Coughing of 12 cases disappeared after 7 days,10 cases′symptoms disappeared after 14-day treatment,and 4 patients′ symptoms disappeared with persistent medication as long as 45 days.Six cases improved on the forth day with inhaled corticosteroids,and pulmonary sputum together with tone and voice bubbles disappeared on the sixth day.Conclusion Montelukast sodium has a good preventive effect on pneumonia with atypical asthma.