心脏X综合征患者ATP负荷^(99m)TC-MIBI心肌灌注显像分析

Adenosine Triphosphate Infusion ^(99m)TC-MIBI Myocardial Perfusion Tomography of Patients with Cardiac Syndrome X

目的总结和分析心脏X综合征患者ATP负荷99mTC-MIBI心肌灌注显像(ATP-MPI)的特点。方法选取临床符合心脏X综合征诊断标准的患者28例,分别行ATP负荷及静息心肌灌注显像,并分析显像结果。结果 11例男性患者中有7例(63.64%)出现异常心肌灌注显像,其中有6例(85.71%)表现为可逆性分布,1例(14.29%)表现为反向再分布;17例女性患者中有12例(70.59%)出现异常心肌灌注显像,其中9例(75%)表现为可逆性缺损,3例(25%)表现为反向再分布。男女性出现异常心肌灌注显像的比例无统计学意义(P>0.05)。结论 ATP负荷99mTC-MIBI心肌灌注显像是评价心脏X综合征冠状动脉微循环病变的一种有效方法。

Objective To clarify the imaging characteristics of adenosine triphosphate （ATP） using ^99m^TC-MIBI SPECT myocardial perfusion imaging in patients with cardiac syndrome X. Methods Twenty-eight patients diagnosed with cardiac syndrome X were enrolled in this study.They all underwent adenosine triphosphate （ATP） using ^99m^TC-MIBI SPECT myocardial perfusion imaging. Results 7 out of 11 male patients with cardiac syndrome X showed abnormal perfusion imaging （63.64%）,among abnormalitites 6 cases （85.71%） of expression was reversible defects, 1 case （14.29%） showed reverse redistribution.17 female patients with cardiac syndrome X had 12 cases （70.59%） with abnormal perfusion defects,among them 9 cases （75%） showed reversible defects and 3 cases （25%） showed reverse redistribution. There was no significant difference between two genders （P〉0.05）. Conclusion Adenosine triphosphate infusion 99mTC-MIBI myocardial perfusion tomography is an effective method in the detection of microcirculatory pathological changes of coronary artery in patients with cardiac syndrome X.