220株铜绿假单胞菌的耐药性分析

Drug-Resistance of 220 Isolates of Pseudomonas Aeruginosa

目的本调查试图通过分析220株铜绿假单胞菌的耐药性来了解铜绿假单胞菌的耐药现状。方法选用220株来自嘉兴市中医院内、外科2008年6月～2010年5月临床标本的铜绿假单胞菌,通过药敏试验测定其对13种抗菌药的耐药性。结果 药敏试验结果显示铜绿假单胞菌对β-内酰胺类、氨基糖苷类和头孢类抗菌药不敏感,而敏感度最高的是阿米卡星(83.2%)和妥布霉素(79.1%)。结论通过本次调查结果可以指导临床治疗铜绿假单胞菌感染的药物选择,同时有助于了解和控制铜绿假单胞菌引起的院内感染的流行情况。

Objective This study aims to investigate drug-resistance status quo of pseudomonas aeruginosa （PA） via analyzing the drug-resistance of 220 isolates of PA. Methods Drug sensitivity assays were performed on 220 isolates of PA from specimens obtained at the department of general surgery in Jiaxing Municipal hospital of Traditional Chinese Medicine between June 2008 and May 2010. Results The PA isolates displayed significant resistance to 13-lactam drugs, aminoglycosides and ceph-based drugs, while they were highly sensitive to amikacin（ 83.2% ）and tobromycin（79.1%）. Conclusion This study has significance in helping select antimicrobial agents for the treatment of PA-induced infections, and provides useful information for the control of PA-induced infections.