摘要
目的:采用HPLC方法测定珍宝丸桂皮醛含量。方法:色谱柱C_(18)(200×4.6mm,5μm);流动相:乙腈-0.05%磷酸(38:62);流速:1mL·min-1;测定波长:290nm。结果:桂皮醛在0.02～0.64?g成线性关系(r=0.9999);回收率为102·2%;五批次珍宝丸桂皮醛含量平均为46.18μg·g^(-1)。结论:采用本法测定珍宝丸桂皮醛的含量,操作简便,准确可靠,可用于制定该药品的质量控制指标之一。
Objective： To determinate cinnamic aldehyde in Shengyang- 11 pill bymeans of HPI.E. Method： A C18 colum （200×4.6mm,5μm）was used with the mobile phase of acetoneitrile- 0.05% phosphoric acid （38：62）, at the detection wavelength of 290nm. The flow rate was 1mL·min- 1 ,and the temperature of colum was 30℃ .Results： Cinnamic aldehyde showed a good linear relation at a range of 0.02-0.64？ g, r = 0.9999.The recovery was 102. 2% and cinnamic aldehyde mean content was 46. 187 g·g-1 lin 5 batchs zhenbao pill. Conclusion ：The method is simple, accurate and specifical. It can be used for determination of cinnamic aldehyde in zhenbao pill.
出处
《中国民族医药杂志》
2011年第5期47-48,共2页
Journal of Medicine and Pharmacy of Chinese Minorities
关键词
蒙药
珍宝丸
桂皮醛
HPLC
Mongolia drug
zhenbao pill
cinnamic aldehyde
HPLC
