292例体检者幽门螺杆菌检测结果分析

Detection of Helicobacter pylori Infection among the Health Screening Population

目的:了解体检人群幽门螺杆菌(Hp)感染情况及分布特征。方法:选取2010年3月至6月间天津医科大学附属肿瘤医院健康体检者29例,以性别和年龄进行分组,应用幽门螺杆菌尿素酶抗体检测试剂盒(胶体金法)快速检测体检人群中幽门螺杆菌感染情况,并对其结果进行统计学分析。结果:292例体检者幽门螺杆菌总感染率为35.3%(103/292),其中男性体检者和女性体检者感染阳性率分别为35.5%(49/138)和35.1%(54/154),男性和女性体检者幽门螺杆菌感染率比较差异无统计学意义(P>0.05);将体检者分为低年龄组(<30岁)、中年龄组(30～55岁)和高年龄组(>55岁)3个实验组,幽门螺杆菌感染率在3个年龄组逐渐增加,感染阳性率分别为14.3%(4/28)、31.9%(44/138)和43.7%(55/126),且低年龄组与高年龄组幽门螺杆菌感染率差异具有统计学意义(P<0.05)。结论:体检人群幽门螺杆菌感染分布与年龄呈正相关,而且与性别无关。

Objective： To investigate the status of Helicobacter pylori （ Hp ） infections and its distribution among the health screening population. Methods： Grouping was conducted based on gender and age. Hp infection was rapidly detected using Helicobacterpylori urease antibody detection kits （ Colloidal Gold method） in the health examination population. The resulting data was statistically analyzed. Results： Hp-positive rate of the 292 individuals that underwent health examinations was 35.3% （ 103/292 ）, and the positive rate in male and female cases were 35.5% （ 49/138 ） and 35.1% （ 54/154 ）, respectively. There were no significant differences in the positive rates between the male and female individuals （P 〉 0.05 ）. The individuals were divided into three experimental groups, namely, the low age group （ 〈30 years ）, the middle age group （30 to 55 years） and the advanced age group （ 〉55 years ）. The Hp-positive rates increased with a direct correlation with age in the low, middle, and advanced age groups, with positive rates of 14.3% （ 4/28 ）, 31.9% （44/138）, and 43.7% （ 55/126 ）, respectively. There were significant differences in the Hp infection rate between the low-age and the advanced-age groups （ P 〈 0.05 ）. Conclusion： The distribution of the Hp infection in the health screening population is positively correlated with patient age, but not with sex.