期刊文献+

浆细胞样树突状细胞与实体肿瘤免疫逃逸 被引量:3

原文传递
导出
摘要 浆细胞样树突状细胞(pDC)以快速分泌Ⅰ型IFN、抑制病毒及细菌等病原入侵的固有免疫应答著称。同时,pDC作为一种专职抗原提呈细胞,能呈递抗原,参与适应性免疫应答。近年来越来越多的研究证明,其分布于实体肿瘤组织内,呈递肿瘤抗原,参与免疫调节,导致肿瘤免疫逃逸。
出处 《现代免疫学》 CAS CSCD 北大核心 2011年第3期262-264,F0003,共4页 Current Immunology
基金 国家自然科学基金资助项目(81071964/H1617) 浙江省人事厅留学回国基金资助项目(J20100113)
  • 相关文献

参考文献27

  • 1Jegalian AG, Facchetti F, Jaffe ES. Plasmacytoid dendritic cells physiologic roles and pathologic states [J]. Adv Anat Pathol, 2009,16:392 -404.
  • 2Lande R, Gilliet M. Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses [J]. Ann N Y Acad Sci,2010,1183:89-103.
  • 3Hartmann E, Wollenberg B, Rothenfusser S, et al. Identifi cation and functional analysis of tumor-infiltrating plasmaey toid dendritic cells in head and neck cancer [J]. Cancer Res, 2003,63 : 6478-6487.
  • 4Perrot I, Blanchard D, Freymond N, etal. Dendritic cells in filtrating human non-small cell lung cancer are blocked at im mature stage [J]. J Immunol, 2007,178:2763- 2769.
  • 5Treilleux I, Blay JY, Bendriss-Vermare N, et al. Dendritic cell infiltration and prognosis of early stage breast cancer [J]. Clin Cancer Res, 2004, 10:7466-7474.
  • 6Zou W, Machelon V, Coulomb-L'Hermin A, et al. Stromal- derived factor-1 in human tumors recruits and alters the func- tion of plasmacytoid precursor dendritic cells [J]. Nat Med, 2001,7 : 1339-1346.
  • 7Sozzani S, Vermi W, Del Prete A, et al. Trafficking proper- ties of plasmacytoid dendritic cells in health and disease [J]. Trends Immunol, 2010,31 : 270 -277.
  • 8Matta BM, Castellaneta A, Thomson AW. Tolerogenie plas- macytoid DC [J]. Eur J Immunol,2010,40 : 2667-2676.
  • 9Mouries J, Moron G, Schlecht G, et al. Plasmacytoid den- dritic cells efficiently cross-prime naive T cells in vivo after TLR activation [J].Blood, 2008, 112:3713-3722.
  • 10Di Pucehio T, Chatterjee B, Smed-Sorensen A, et al. Direct proteasome independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility com- plex class I [J]. Nat Immunol, 2008, 9:551-557.

二级参考文献39

  • 1Barron MA, Blyveis N, Palmer BE, et al. Influence of plasma viremia on defects in number and immunophenotype of blood dendritic cell subsets in human immunodeficiency virus 1-infected individuals [ J]. J Infect Dis, 2003,187 (1): 26-37.
  • 2Mohty M, Isnardon D, Vey N, et al. Low blood dendritic cells in chronic myeloid leukaemia patients correlates with loss of CD34+/CD38- primitive haematopoietic progenitors [J]. Br J Haematol, 2002, 119 (1): 115- 118.
  • 3Wertheimer AM, Bakke A, Rosen HR. Direct enumeration and functional assessment of circulating dendritic cells in patients with liver disease [J]. Hepatology, 2004, 40(2):335 - 345.
  • 4Matsuda H, Suda T, Hashizume H, et al. Alteration of balance between myeloid dendritic cells and plasmacytoid dendritic cells in peripheral blood of patients with asthma [J]. Am J Respir Crit Care Med, 2002, 166 (8):1 050- 1 054.
  • 5Facchetti F, Vermi W, Mason D, et al. The plasmacytoid monocyte/interferon producing cells [ J ]. Virchows Arch,2003, 443 (6): 703- 717.
  • 6Pashenkov M, Huang YM, Kostulas V, et al. Two subsets of dendritic cells are present in human cerebrospinal fluid [J].Brain, 2001, 124 (Pt 3): 480-492.
  • 7Vermi W, Facchetti F, Rosati S, et al. Nodal and extranodal tumor-forming accumulation of plasmacytoid monocytes/interferon-producing cells associated with myeloid disorders [J]. Am J Surg Pathol, 2004, 28 (5): 585- 595.
  • 8Van Krinks CH, Matyszak MK, Gaston JS. Characterization of plasmacytoid dendritic cells in inflammatory arthritis synovial fluid [ J ]. Rheumatology (Oxford), 2004, 43 (4):453 - 460.
  • 9Barchet W, Cella M, Odermatt B, et al. Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo [ J ]. J Exp Med,2002, 195 (4): 507 - 516.
  • 10Krug A, French AR, Barchet W, et al. TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function [J]. Immunity, 2004, 21 (1): 107- 119.

共引文献2

同被引文献36

  • 1韩超峰,曹雪涛.肿瘤诱导的树突状细胞功能缺陷及其机制[J].中国肿瘤生物治疗杂志,2005,12(2):89-93. 被引量:12
  • 2Melchiorre Cervello,Daniela Foderà,Ada Maria Florena,Maurizio Soresi,Claudio Tripodo,Natale D'Alessandro,Giuseppe Montalto.Correlation between expression of cyclooxygenase-2 and the presence of inflammatory cells in human primary hepatocellular carcinoma: Possible role in tumor promotion and angiogenesis[J].World Journal of Gastroenterology,2005,11(30):4638-4643. 被引量:21
  • 3Steinman RM. The dendritic cell system and its role in immuno?genicity. Annu Rev Immunol1991; 9: 271-96.
  • 4Giboa E. DC-based cancer vaccines. J Clin Invest 2007; 117: 1195-203.
  • 5Casati A, Zimmermann VS, Benigni F, Bertilaccio MT, Bellone M, Mondino A. The immunogenicity of dendritic cell-based vac?cines is not hampered by doxorubicin and melphalan administra?tion. J Immunol2005; 174(6): 33 \ 7-25.
  • 6Feng H, Zeng Y, Graner MW, Likhacheva A, Katsanis E. Exog?enous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate antitumor immunity. Blood 2003; 101(1): 245-52.
  • 7Choi GS, Lee MH, Kim SK, Kim CS, Lee HS, Im MW, et al. Combined treatment of an intra tumoral injection of dendritic cells and systemic chemotherapy (Paclitaxel) for murine fibrosar?coma.Yonsei Med J 2005; 46(6): 835-42.
  • 8Zheng H, Li Z. Cutting edge: Cross-presentation of cell-associ?ated antigens to MHC class I molecule is regulated by a major transcription factor for heat shock proteins. J Immunol 2004; 173(10): 5929-33.
  • 9Steinman RM, Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. I, Morphology, quantitation, tissue distribution [ J]. J Exp Med, 1973, 137(5) :1142-1162.
  • 10Casati A, Zimmermann VS, Benigni F, et al. The immu- nogenicity of dendritic cell-based vaccines is not hampered by doxorubicin and melphalan administration[ J]. J Immu- nol, 2005, 174(6) :3317-3325.

引证文献3

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部