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结核病易感相关免疫基因研究进展 被引量:1

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摘要 结核易感性与遗传、环境、年龄、性别、HIV感染、营养缺乏、BCG接种和吸烟等宿主因素有关[1]。其中,遗传因素是影响结核易感性的重要因素[2],可以影响结核分枝杆菌(Mycobacterium tuberculosis,Mtb)与宿主免疫系统间的平衡关系,最终导致不同的感染结局。以家族为基础的连锁分析(1inkagean alysis)和病例一对照为基础的关联分析(association analysis)。
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 2011年第5期472-476,共5页 Chinese Journal of Microbiology and Immunology
基金 国家“十一五”传染病重大专项(2008ZXl0003011) 中国博士后基金(20090450649)
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参考文献41

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二级参考文献9

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