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曲马多与舒芬太尼硬膜外术后镇痛的比较 被引量:2

A comparison of sufentanil or tramadol in combination with ropivacaine for epidural postoperative analgesia
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摘要 目的:比较罗哌卡因复合曲马多或舒芬太尼硬膜外术后镇痛的效果及不良反应。方法:选择40例腰硬联合阻滞下行腹式子宫切除术的病人,观察术后24小时内的镇痛效果、不良反应及辅助药物的使用情况。结果:舒芬太尼组与曲马多组镇痛效果相似,但曲马多组术后24h恶心、呕吐发生率较高,与舒芬太尼组比较差异有显著性(p﹤0.05),其他副反应如呼吸抑制、嗜睡、心动过缓等两组比较无明显差异(p﹥0.05)。结论:舒芬太尼或曲马多复合罗哌卡因均可提供良好的硬膜外术后镇痛效果,硬膜外注射舒芬太尼复合罗哌卡因镇痛效果良好,不良反应少。 Objective:To compare the efficacy and adverse effects of tramadol or sufentanil plus ropivacaine for postoperative analgesia.Methods:Forty ASAⅠ-Ⅱpatients aged 20-60 years,weighting 45-75kg undergoing abdominal hysterectomy surgery were randomly allocated into two groups.In groupⅠpatients received tramadol 100mg plus 0.2% ropivacaine and droperidol 2.5mg through epidural catheter;In groupⅡpatients received sufentanil 15μg plus 0.2% ropivacaine and droperidol 2.5mg.Postoperative pain was recorded at postoperative times 2h,4h,6h,8h,12h,18h and 24h and side effects were noted.Results:There were no differences in postoperative analgesic effect between two groups .The incidence of nausea and vomiting was higher in group Ⅰin the first 24 hours.Conclusion:Sufentanil combined with ropivacaine is effective and lower incidence of adverse effects for epidural postoperative analgesia.
出处 《医学信息(中旬刊)》 2011年第6期2458-2459,共2页 Medical Information Operations Sciences Fascicule
关键词 舒芬太尼 曲马多 罗哌卡因 术后镇痛 Sufentanil Tramadol Ropivacaine Postoperative analgesia
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  • 1Katz WA.Pharmacology and clinical experience with tramadol in osteoarthritis.Drugs,1996,52(Suppl 3):39-47.
  • 2Houmes RJ,Voets MA,Verkaaik A,et al.Efficacy and safety of tramadol versus morphine for moderate and severe postoperative pain with special regard to respiratory depression.Anesth Analg,1992,74:510-514.
  • 3Tarradell R,Polo,Farre M,et al.Respiratory and analgesic effects of meperidine and tramadol in patients undergoing orthopedic surgery.Methods Find Exp Clin Pharmacol,1996,18:211-218.

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