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替罗非班在缺血性脑卒中的应用 被引量:1

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摘要 替罗非班非多肽类血小板糖蛋白IIb/IIIa受体拮抗剂,通过抑制血小板聚集的最后共同途径而抑制血小板聚集和血栓形成。因此,替罗非班可通过阻止血栓的生长,产生内源性溶栓;通过竞争性抑制纤维蛋白原在血小板间形成间桥,阻止血栓的再形成。目前,替罗非班在急性缺血性脑卒中的治疗中发挥越来越重要作用。
出处 《医学信息(中旬刊)》 2011年第6期2841-2842,共2页 Medical Information Operations Sciences Fascicule
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  • 1Junghans U,Seitz RJ,Aulich A,et al.Bleeding risk of tirofiban:A nonpeptide GPIIb/IIIa platelet receptor antagonist in progressive stroke:An open pilot study.Cerebrovasc Dis,2001,12:308-12.
  • 2Seitz RJ,Hanzavi M,Junghans U,et al.Thromblysis with recombinant tissue plasminogen activator and tirofiban in stroke:preliminary observations.Stroke,2003,34(8):1932-1935.
  • 3Salvatore Mangiafico,Martino Cellerini,Patrizia Nencini,et al.Intravenous Glycoprotein IIb/IIIa Inhibitor (Tirofiban) followed by Intra-Arterial Urokinase and Mechanical Thrombolysis in Stroke.AJNR Am J Neuroradiol,2005,26:2595-2601.
  • 4Deshmukh,Vivek R,Fiorella,David J,Albuquerque,Felipe C,et al.Intra-arterial Thrombolysis for Acute Ischemic Stroke:Preliminary Experience with Platelet Glycoprotein IIb/IIIa Inhibitors as Adjunctive Therapy.Neurosurgery,2005,56(1):46-55.
  • 5Straub S,Junghans U,Jovanovic V,Wittsack HJ,Seitz RJ,Siebler M.Systemic thrombolysis with recombinant tissue plasminogen activator and tirofiban in acute middle cerebral artery occlusion.Stroke,2004,35(3):705-709.
  • 6Mangiafico S,Cellerini M,Nencini P,Gensini G,Inzitari D.Intravenous glycoprotein IIb/IIIa inhibitor (tirofiban) followed by intra-arterial urokinase and mechanical thrombolysis in stroke.AJNR Am J Neuroradiol,2005,26:2595-601.
  • 7Haerten K,Krabbe C,Raiber M.Efficacy and safety of treatment of acute ischemic stroke with glycoprotein IIb/IIIa receptor blocker in routine clinical practice.Dtsch Med Wochenschr,2004,129(12):607-610.
  • 8Alfonso Ciccone,Iosief Abraha,Ignazio Santilli.Glycoprotein IIb-IIIa Inhibitors for Acute Ischemic Stroke.Stroke,2007,38:1113-1114.
  • 9Junghans U,Siebler M.Cerebral microembolism is blocked by tirofiban,a selective nonpeptide platelet glycoprotein IIb/IIIa receptor antagonist.Circulation,2003,107:2717-2721.
  • 10Seitz RJ,Meisel S,Moll M,Wittsack HJ,Junghans U,Siebler M.The effect of combined thrombolysis with rtPA and tirofiban on ischemic brain lesions.Neurology,2004,62:2110-2.

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