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miRNA-30c的研究进展 被引量：6

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摘要 miRNA是近年来发现的一类长度为18～24个核苷酸的可调控基因表达的非编码小分子RNA,它主要通过与靶标基因3′UTR的完全或不完全配对,降解靶标基因mRNA或抑制其翻译,从而参与调控个体发育、细胞凋亡、增殖及分化等生命活动。miRNA-30c作为miRNAs中的一员,不仅在多种组织中表达,而且许多研究还表明它可能与某些肿瘤的发生发展存在一定的关系。现对miRNA-30c的相关研究进展作一综述。
作者 徐晓峰 周怀君
机构地区 东南大学医学院 南京大学医学院附属鼓楼医院妇产科
出处 《东南大学学报（医学版）》 CAS 2011年第3期514-518,共5页 Journal of Southeast University(Medical Science Edition)
基金 江苏省卫生厅面上课题(H200942)
关键词 MICRORNA miRNA-30c 肿瘤 文献综述
分类号 R73 [医药卫生—肿瘤] R730.2 [医药卫生—肿瘤]
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二级参考文献73

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共引文献4

同被引文献61

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引证文献6

二级引证文献19

东南大学学报（医学版）
2011年 第3期

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