昆虫飞行肌细胞凋亡的分子生物学研究进展

Progress of molecular biology researches in insect flight muscle cell apoptosis

细胞凋亡是多细胞生物体内由激素刺激,基因调控,蛋白调节的一个主动的程序化死亡过程,对生物体特定组织功能的发生、发展、衰老及退化等具有重要作用。而昆虫飞行肌细胞凋亡对昆虫迁飞行为尤为重要,它直接决定迁飞性昆虫能否选择更适宜的寄主植物和生活条件,进而影响到对农作物的危害地域和严重程度。本文在近年来昆虫细胞凋亡的研究基础上,从分子生物学的角度,综述了调控昆虫飞行肌细胞凋亡的相关基因和蛋白质的研究进展,探讨了昆虫飞行肌细胞凋亡发生与调控的分子生物学机制。

Cell apoptosis is a process causing cell death in multi-cellular organisms that is stimulated by hormones and regulated and modulated by specific genes and proteins.It plays an important role in germinating,developing,aging and the degeneration of certain cells and tissues.Flight muscle apoptosis is especially important in insects that migrate over long distances.The timing of this process determines whether such insects can locate preferable plant hosts or better habitats and indirectly affects the nature of the damage such pests inflict on agricultural plant crops.In this article,we summarize the genes and proteins which encode or regulate parts of insects＇ flight muscle and discuss the molecular mechanism of flight muscle apoptosis and its role in the regulation of insect migration.