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甲氨蝶呤治疗银屑病的临床应用 被引量:4

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摘要 银屑病是反复发作的、T淋巴细胞介导的慢性炎症性皮肤病。自1972年美国食品药品监督管理局(FDA)批准甲氨蝶呤(MTX)治疗银屑病以来,已有40多年历史。临床调查资料显示,约有44%的中重度银屑病患者系统使用过MTX治疗,在2009年美国银屑病基金会共识会议上仍推荐为治疗银屑病相对安全有效的药物,主要适用于外用药及其他系统治疗如PUVA或维A酸效果不佳的中至重度寻常性银屑病,
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2011年第6期457-460,共4页 Chinese Journal of Dermatology
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