摘要
在医药工业中,2-溴乙氧基苯是用于合成度米芬等医药的重要中间体。以乙二醇苯醚和三溴化磷为原料,在无溶剂条件下采用相转移催化反应,考察了催化剂、反应温度、反应时间、原料配比对反应收率的影响。
In Pharmaceutical Industry 2-Bromoethoxybenzene is an important Intermediates used for synthesis of Domiphen.This paper studyed on synthesis of 2-Bromoethoxybenzene from Ethylene glycol phenyl ether and phosphorus tribromide in solvent-free conditions using phase transfer catalyst.The influence of catalyst,reaction temperature,reaction time,and raw materials ratio on yield was investigated.
出处
《上海化工》
CAS
2011年第6期4-6,共3页
Shanghai Chemical Industry
关键词
乙二醇苯醚
三溴化磷
相转移催化
2-
溴乙氧基苯
Ethylene glycol phenyl ether
Phosphorus tribromide
Phase transfer catalyst
2-Bromoethoxybenzene
