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药物综合治疗对阵发性房颤患者左心房舒张期功能的影响 被引量:1

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摘要 目的探讨阵发性房颤(PAF)患者左心房舒张期功能变化及药物综合治疗的效果。方法对83例PAF患者(PAF组)于确诊后予营养心肌及血管紧张素转换酶抑制剂等药物综合治疗,疗程3个月;治疗前后分别采用彩色多普勒超声心动图分析系统测定左心房舒张功能指标,并随访判定疗效。设80例健康体检者为对照组。结果与对照组比较,PAF组治疗前二尖瓣血流舒张早期最大流速(EV)降低、二尖瓣血流心房收缩期最大流速(AV)增大、EV/AV减小、左心房等容舒张时间(LVRT)延长、左心房内径(LAD)增加(P均<0.05),而左心房射血分数(LAEF)无显著差异;PAF组治疗后上述左心房功能指标显著改善,且总有效率达89.39%。结论 PAF患者存在明显左心房舒张期功能障碍,药物综合治疗近期效果确切,远期疗效有待进一步验证。
机构地区 东莞市康华医院
出处 《山东医药》 CAS 北大核心 2011年第23期30-31,共2页 Shandong Medical Journal
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