持续气道正压通气辅助治疗OSAS并高血压32例效果观察被引量：3

下载PDF

导出

摘要目的观察持续气道正压通气(CPAP)辅助治疗阻塞性睡眠呼吸暂停低通气综合征(OSAS)并高血压的临床效果。方法将同期收治的64例OSAS并高血压患者随机分为观察组和对照组各32例,两组均予常规降压药物等治疗,在此基础上观察组于晚间加用CPAP治疗,疗程均为12周。分别于治疗前后检测睡眠呼吸暂停低通气指数(AHI)、最低血氧饱和度(LSaO2)、最长呼吸暂停时间(LAT)并监测血压参数。结果两组治疗后AHI、LSaO2、LAT及血压参数均较治疗前显著改善,尤以观察组为著(P<0.05或0.01)。结论 CPAP辅助治疗OSAS并高血压可同时改善气体交换功能及增强降压效果。

作者刘静

机构地区天津市第五中心医院

出处《山东医药》 CAS 北大核心 2011年第23期100-101,共2页 Shandong Medical Journal

关键词持续气道正压通气降压药物高血压阻塞性睡眠呼吸暂停低通气综合征

分类号 R765.2 [医药卫生—耳鼻咽喉科]

引文网络
相关文献

参考文献8

1韩德民,叶京英,王军,杨庆文,林宇华,王江泳.上气道压力测定对阻塞性睡眠呼吸暂停综合征阻塞部位定位诊断研究[J].中华耳鼻咽喉科杂志,2001,36(4):301-304. 被引量：66
2Dhillon S,Chung SA,Fargher T,et al.Sleep apnea,hypertension,and effects of continuous positive airway pressure[J].Am J Hypertens,2005,18(5):594-600.
3上海市医学会呼吸病学分会睡眠呼吸疾病学组.上海市30岁以上人群阻塞性睡眠呼吸暂停低通气综合征流行病学调查[J].中华结核和呼吸杂志,2003,26(5):268-272. 被引量：281
4Sayk F,Booker C,Teckentrup C,et al.To dip or not to dip:on theplIysiology of blood pressure decrease dinocturnal sleep inhealtlIy humans[J].Hypertension,2007,49(6):1070-1076.
5叶京英,韩德民,王军,王小轶,王江泳.睡眠呼吸障碍患者上气道形态与睡眠监测观察[J].中国耳鼻咽喉头颈外科,2005,12(8):519-522. 被引量：12
6Tun Y,Hida W,Okabe S,et al.Can Nasal Continuous Positive AirwayPressure Decrease Clinic Blood Pr essure in Patients with obstmctive sleep apnea[J].Tohoku J Exp Med,2003,201(3):181-190.
7李菁,李峥,李五一.阻塞性睡眠呼吸暂停低通气综合征患者行为干预的研究进展[J].中华护理杂志,2007,42(6):541-543. 被引量：36
8Hsu PP,Tan BY,Chan YH,et al.Clinical predictors in obstructive sleep apnea patients with computer assisted quantitative videoendoscopic upper airway analysis[J].Laryngoscope,2004,114(5):791-799.

二级参考文献47

1Young T, Palta M, Dempsey J, et al. The occurrence of sleepdisordered breathing among middle-aged adults. N Engl J Med,1993, 328 : 1230-1235.
2Bixler EO, Vgontzas AN, Ten Have T, et al. Effects of age on sleep apnea in men: I. Prevalence and severity. Am J Respir Crit Care Med, 1998, 157: 144-148.
3Bixler EO, Vgontzas AN, Lin HM, et al. Prevalence of sleepdisordered breathing in women: effects of gender. Am J Respir Crit Care Med, 2001, 163(3 Pt 1 ) : 608-613.
4Duran J, Esnoala S, Rubio R, et al. Obstructive sleep apneahypopnea and related clinical features in population-based sample of subjeets aged 30 to 70yr. Am J Respir Crit Care Med, 2001, 163(3Pt 1 ) : 685-689.
5Bearpark H, ERiott L, Grunstein R, et al. Snoring and sleep apnea:a population study in Australian men. Am J Respir Crit Care Med,1995, 151 : 1459-1465.
6Olson LG, King MT, Hensley MJ, et al. A community study of snoring and sleep-disordered breathing. Prevalence. Am J Respir Crit Care Med. 1995. 152: 711-716.
7Ohayon MM, Guilleminault C, Priest RG, et al. Snoring and breathing pauses during sleep : telephone interview survey of a United Kingdom population sample. BMJ, 1997, 314: 860-863.
8Ip M, Lam B, Lauder IJ, et al. A community study of sleepdisordered breathing in middle-aged Chinese men in Hong Kong.Chest, 2001, 119: 62-69.
9Puvanendran K,Goh KL.From snoring to sleep apnea in a Singapore population.Sleep Res Online,1999,2:11-14.
10Gottlieb DJ,Yao Q,Redline S,et a1.Does snoring predict sleepiness independently of apnea and hypopnea frequency?Am J Respir Crit Care Med,2000,162(4 Pt 1):1512.1517.