胃肠道黏液腺癌的临床病理及其预后分析

Clinical pathological features of gastrointestinal mucinous adenocarcinoma and its prognosis

目的分析胃肠道黏液腺癌的临床病理特点及其预后。方法选择确诊为胃肠道黏液腺癌的患者80例(观察组)和同期治疗的胃肠道非黏液腺癌的癌症患者80例(对照组),比较两组的临床病理资料。结果观察组,尤其是在Ⅲ+Ⅳ期患者中,肿瘤直径、有淋巴结转移例数、腹膜播散例数以及肿瘤浸出浆膜例数明显多于对照组(P<0.05),而且其根治切除例数和生存率明显低于对照组。结论胃肠道黏液腺癌的临床病理特点提示,早期诊断、早期治疗,对癌灶行根治性手术是治疗胃肠道黏液腺癌最好的方法。

Objective To assess the relationship between the clinical pathological features of gastrointestinal mucinous adenocarcinoma and its prognosis.Methods The clinical data of patients with gastrointestinal mucinous adenocarcinoma（observation group）, were analyzed, as well as those of cases with the other kinds of gastrointestinal cancer（control group）.Results In observation group, especially in patients with stage Ⅲ and stage Ⅳ of gastrointestinal mucinous adenocarcinoma, the case numbers of tumor diameter, lymphatic metastasis, peritoneal dissemination and invading beyond serosa were higher（P0.05）,but the number of cases with radical resection and survival rate were significantly lower as compared with the control group.Conclusion According to the pathological features in this study, early diagnosis and treatment and radical surgery of cancer foci should be made for a better prognosis of gastrointestinal mucinous adenocarcinoma.