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高渗应激早期伤寒沙门菌RpoE调节因子对基因表达的影响 被引量：2

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摘要 伤寒沙门菌是一种革兰阴性肠道致病菌,常通过污染的食物进入体内,可造成严重全身性感染[1-2].作为食源性致病菌,必须遭遇人体消化道的高渗环境,但目前对其克服高渗应激的具体机制尚不清楚.RpoE调节因子由rpoE基因编码,是肠杆菌科细菌中一个重要的σ因子,在大肠杆菌响应高渗应激时发挥着重要的作用[3],在伤寒沙门菌中也应当十分重要.
作者 杜鸿 倪斌 王敏 罗哲 谢新民 李安平 黄新祥
机构地区 江苏大学医学技术学院生物化学研究室 苏州大学附属第二医院检验科 江苏大学医学技术学院生物化学研究室
出处 《中华预防医学杂志》 CAS CSCD 北大核心 2011年第6期564-566,共3页 Chinese Journal of Preventive Medicine
基金 国家自然科学基金（30870095）
关键词 伤寒沙门菌 高渗环境 调节因子 基因表达 应激 严重全身性感染 早期 食源性致病菌
分类号 R346 [医药卫生—基础医学]
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参考文献9

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二级参考文献19

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共引文献13

同被引文献21

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中华预防医学杂志
2011年 第6期

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