异丙酚、安氟醚及其复合组对麻醉后期恢复的影响

The effectofpropofol, enflurane and their com bination on the postoperative recovery

目的 采用双盲法观察不同麻醉维持方法麻醉后期的恢复情况。方法 ３０ 例择期手术的病人，ＡＳＡ Ⅰ～Ⅱ级，随机分为三组：安氟醚组、异丙酚组及复合组，每组１０ 例。安氟醚组以１％～２％ 安氟醚吸入维持麻醉，异丙酚组以注射泵经静脉持续输注异丙酚６～１２ｍ ｇ·ｋｇ－ １／ｈ 维持麻醉，复合组吸入１％ 安氟醚并静脉输注异丙酚６～９ｍ ｇ·ｋｇ－ １／ｈ。结果 安氟醚组的术后呼吸、吞咽反射、呼之睁眼恢复时间明显短于其它二组（ Ｐ＜ ０．０５ 或Ｐ＜ ０．０１）；术后拔管时间复合组明显长于其它二组（Ｐ＜ ０．０１）；呼吸道梗阻的发生率三组相同；停药－定向力恢复时间三组相同，但拔管－定向力恢复时间复合组明显高于其它二组（ Ｐ＜ ０．０５）。结论 从术后恢复角度看。

Objective Observing the postoperative recovery for m aintenance of anesthesia w ith double blind m ethod.Methods 30 patients (ASA Ⅰ～Ⅱ) w ith selective operation allocated random ly into three groups: enflurane group, propofolgroup and com binative group. Every group had 10 patients. In the enflurane group anesthesia w asm aintained w ith 1% ～2% enflurane, in the propofolgroup it w as w ith continuous intravenous infusion of propofol6～12 m g/kg and in the com binative group itw asm aintained w ith both agents.Results The recovery tim eofspontaneous breathing, sw allow ing and opening the eyes by prom pting w ere longerin both propofoland com bi- native groups than in enflurane group ( P < 0.05 or P < 0.01). Extubation w as delayed in the com binative group ( P< 0.05). The occurrency ofrestlessness after extubation w as higherin the com binative group than the other tw o groups ( P< 0.01). The occurency ofairw ay, obstruction, the intervalbetw een w ithdraw ing the anesthetics and recovery of orientation w as the sam e in all groups, but the intervalbetw een extubation to recovery oforientation w as longer in the com bina- tive group than other tw o groups ( P< 0.05).Conclusion Itis unreasonable for m aintenance of anesthesia w ith the com bination ofenflurane and intravenous propofolaccording to the postopera- tive recovery.