摘要
通过较大样本比较胎儿纤维结合素(FFN)和Bishop评分对预测足月孕妇引产的意义。对象为产科有引产指征和择期引产的足月孕妇共105例。方法:引产当日行阴道内诊前常规准备,用生理盐水3ml冲洗宫颈外国滞留10分,抽取冲洗后的盐水送检FFN水平。临床检查得出Bishop评分。结果:105例受试者中,剖宫产13例,≤24小时引产成功58例,>24小时引产成功34例。FFN预测孕妇引产成功的特异性为90%,敏感性为77%,阳性和阴性预测值分别为87%和81%。Bishop评分预测孕妇引产成功的相应指标为72%、68%、79%和59%。结论:胎儿纤维结合素作为独立的客观标志预测足月孕妇引产是否成功优于Bishop评分。
Objective: To compare the fetal fibronectin (FFN) with Bishop score for the prediction of successful labor induction. Methods: Term pregnant woman undergoing labor induction had a sample from the cervicovaginal mucus tested with a blinded quantitative determination of the FFN concentration before the initiation of prostaglandin (positive≥120 ng/ml). The study population (105 cases) was devided into two groups: women delivering within 24 hours after initiation of prostaglandin and women giving birth >24 hours. Results: of the overall 105 subjects,58 women delivering within 24 hew after initiation of prostaglandin and 34 women giving birth >24 hours, 67 had positive and 38 had negative FFN results. Patients with a positive result had a lower cesarean section rate (10% vs 16%, P<0 .05) and higher successful labor induction rate within 24 hours (87% vs 19 %, P< 0. 05). Conclusion: The specificity, sensitivity, positive and negative accuracy rates of FFN was 90%,77%,87% and 81% respectively,better than the corresponding value of Bishop score (72%, 68%, 79% and 59%) for the prediction of successful labor induction.
出处
《天津医药》
CAS
1999年第12期726-728,共3页
Tianjin Medical Journal