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丙戊酸钠两次LD_(50)测定结果的对比研究

Comparison of two LD_(50) values of sodium valproate
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摘要 The two intravenous toxicity data for sodium valproate in mice,generated by using classical LD 50 test,were compared.Though there were great differences between the two acute toxicity test in testing time,body weight,dosage,class interval,and death distribution etc.the two LD 50 values were very close (1\^14 and 0\^96 g/kg).It indicated that LD 50 value as an evaluation index is still steady and representative. The two intravenous toxicity data for sodium valproate in mice,generated by using classical LD 50 test,were compared.Though there were great differences between the two acute toxicity test in testing time,body weight,dosage,class interval,and death distribution etc.the two LD 50 values were very close (1\^14 and 0\^96 g/kg).It indicated that LD 50 value as an evaluation index is still steady and representative.
出处 《中国公共卫生》 CAS CSCD 北大核心 1999年第12期1138-1138,共1页 Chinese Journal of Public Health
关键词 丙戊酸钠 LD50 测定 对比研究 LD_(50) Sodium valproate

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