连续旋转环状色谱的数学模型参数分析

Analysis of Mathematical Model Parameters for Continuous Rotary Annular Chromatography

连续旋转环状色谱用数学模型模拟时，模拟结果的精确度和所采用参数的“灵敏”程度有关。为此，探讨了相平衡常数、相间传质系数、弥散返混系数等对色谱峰质量浓度最高点位置角度（保留值）、分离度、峰宽和产率等参数的灵敏度并对它们逐一进行了分析。认为相平衡关系对分离效果最为敏感。筛选吸附量大。

The curves of analysis solution of mathematical model for continuous rotary annular chromatography (CAC) coincide with experimental results well, but some points are derived from theoretical values due to the errors from experimental method. The width and the angles of maximum mass concentration solution at outlet (retention number), except for the other experimental conditions, depend on phase equilibrium coefficient and transfer functions. Because the precision of model parameters is strongly affected by the correction of experimental method, the sensitivities of phase equilibrium coefficients and transfer functions have been studied, in which the phase equilibrium coefficient is the key parameters to improve the separation effect of CAC process.