钌配合物催化苯乙酮的氢转移还原反应的研究

A study on hydrogen transfer reduction of acetophenone catalyzed by ruthenium complexes

在空气气氛条件下，对钌配合物催化苯乙酮的氢转移还原反应作了详细的考察，取得了较好的结果，使反应更加方便快捷。考察了ＲｕＣｌ３、ＲｕＣｌ３／Ｌｎ［Ｌｎ＝ 邻苯二胺（简称ＰＤＡ）、邻氨基酚（简称ＡＰＯ）、邻氨基苯甲酸（简称ＡＢＡ）、２，２′－联吡啶（简称ＢＩＰＹ）］及ＲｕＣｌ２（ＰＰｈ３）３ 这６ 种催化剂对苯乙酮还原为苯乙醇的催化效果。实验表明，在异丙醇作为溶剂及提供氢源的情况下，以少量ＮａＯＨ 作为助催化剂，ＲｕＣｌ３／ＡＰＯ 催化体系具有非常高的催化活性，产物产率很高。这说明配体邻氨基酚与ＲｕＣｌ３

Hydrogen transfer reduction of acetophenone with propan 2 ol catalyzed by ruthenium complexes were investigated carefully in air.Good results were obtained and the reactions performed more quickly and conveniently.The catalytic behavior of RuCl 3,RuCl 3/L n [L n = o phenylene diamine (PDA); o aminophenol (APO); o aminobenzoic acid (ABA);2,2′ dipyridyl (BIPY)] and RuCl 2(PPh 3) 3 on hydrogen transfer reduction of acetophenone with propan 2 ol was investigated.The experimental results show that RuCl 3/APO exhibits high catalytic activity and the yield of the product is the highest in these catalysts by using 2 propanol as hydrogen donor and NaOH as co catalyst.It is indicated that the APO may complex with RuCl 3 which leads to good results for the hydrogen transfer of acetophenone.