卤代芳氧基酰氧基烃基膦酸及其酯的合成与生物活性

The synthesis and biological properties of α halogenated phenoxy carbonyloxy alkyl phosphonic acids and esters

报道以２，４－二氯苯酚、氯代乙酸或α－氯代丙酸乙酯为起始原料合成１２ 种卤代芳氧基酰氧基烃基膦酸或其酯的方法及目标化合物的除草活性。

A series of twelve new compounds,α halogenated phenoxy carbonyloxy alkyl phosphonic acids and their esters,have been synthesized,starting from 2,4 dichlorophenol,acetic acid or ethyl 2 chloroacetate,followed by indirect hydrolysis to give the corresponding phosphonic acids.The biological activity and its relationship with the structure of the title compounds have been discussed.