期刊文献+

外周NMDA受体在慢性痛中的作用及机制研究 被引量:1

下载PDF
导出
摘要 疼痛是组织损伤或潜在的组织损伤所引起的不愉快的感觉或情感体验(IASP,1994)。在正常生理状况下,疼痛是警示躯体受到威胁的警报信号,是生命不可缺少的一种特殊保护功能。但是,在病理性条件下(如损伤或炎症),疼痛已经不再是一种警报信号,而是逐渐发生持续慢性化,表现出:
出处 《神经解剖学杂志》 CAS CSCD 北大核心 2011年第3期340-343,共4页 Chinese Journal of Neuroanatomy
基金 国家自然科学基金(30970971)
  • 相关文献

参考文献45

  • 1Song X J, Hu SJ, Greenquist KW, et al. Mechanical and thermal hyperalgesia and ectopic neuronal discharge after chronic compression of dorsal root ganglia [ J]. J Neurophysiol, 1999, 82:3347 - 3358.
  • 2Amir R, Michaelis M, Devor M. Membrane potential oscillations in dorsal root ganglion neurons role in normal electrogenesis and neuropathic pain [J]. J Neurosci, 1999, 19:8589 -8596.
  • 3Devor M. Unexplained peculiarities of the dorsal root ganglion [ J ]. Pain, 1999, Suppl 6:$27 -35.
  • 4Kutsuwada T, Kashiwabuchi N, Mori H, et al. Molecular diversity of the NMDA receptor channel [J]. Nature, 1992, 358 : 36 -41.
  • 5Monaghan DT, Bridges RJ, Cotman CW. The excitatory aminoacid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system [J]. Annu Rev Pharmacol Toxicol, 1989, 29:365 - 402.
  • 6Monyer H, Sprengel R, Schoepfer R, et al. Heteromeric NMDA receptors: molecular and functional distinction of subtypes [ J]. Science, 1992, 256 : 1217 - 1221.
  • 7Das S, Sasaki YF, Rothe T, et al. Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A [J]. Nature, 1998, 393:377 -381.
  • 8Sun L, Margolis FL, Shipley MT, et al. Identification of a long variant of mRNA encoding the NR3 subunit of the NMDA receptor: its regional distribution and developmental expression in the rat brain [J]. FEBS Lett, 1998, 441:392 -396.
  • 9Dingledine R, Borges K, Bowie D, et al. The glutamate receptor ion channels [J]. Pharmacol Rev, 1999, 51:7-61.
  • 10Furukawa H, Singh SK, Maucusso R, et al. Subunit arrangement and function in NMDA receptors [J]. Nature, 2005, 438: 185- 192.

同被引文献8

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部