非小细胞肺癌生存分析及预后相关因素研究

Survival analysis and prognosis of lung cancer related factors

目的:探讨影响非小细胞肺癌(NSCLC)患者生存与预后因素的关系。方法:调查研究本院从2005-01/2010-09治疗的275例NSCLC患者的临床资料,并对其年龄、病理类型、临床分期、淋巴结中的微转移灶和治疗方式对预后的影响进行调查,并分析其对患者的预后因素。结果:本组患者在家族史、临床分期等因素为患者治疗后较差的生存预后因素,而治疗方式的选择为最大影响因素。本组患者选用手术+化疗,化疗+放疗,单纯化疗和对症治疗4组,在生存率比较中四组患者存在统计学差异(P<0.05)。而患者的年龄、临床分期、淋巴结中的微转移灶、病理类型对患者预后的影响有统计学意义。结论:治疗方式是影响NSCLC预后的重要因素。

AIM： of non-small cell lung cancer（non a smal1eelllungeaneer,NSCLC） patients with survival analysis and prognostic factors.METHODS： The research l our hospital from 2005 to September 2010 on the treatment of 275 cases of clinical data of patients with NSCLC,and its age,pathological type,clinical stage,lymph node micrometastasis on prognosis and treatment Investigation of influence,and to analyze the prognostic factors for patients.RESULTS： The patients in the family history,clinical stage and other factors after treatment for patients with poor prognostic factors for survival.The treatment of choice for the greatest impact factor.This group of patients selected surgery plus chemotherapy,chemotherapy＋radiotherapy,chemotherapy and symptomatic treatment 4,in the survival rates of patients in the four groups was significantly different（P〈0.05）.The patient＇s age,clinical stage,lymph node micrometastasis in pathological type on the prognosis of patients was statistically significant.CONCLUSION： The treatment of non-small cell lung cancer is an important prognostic factor.