不同年龄段儿童社区获得性大叶性肺炎病原学分析

The etiology analysis of community-acquired lobar pneumonia in different stages of children

目的探讨近2年儿童社区获得性大叶性肺炎的病原学特点及其变化,指导临床治疗。方法回顾性分析住院治疗的106例儿童大叶性肺炎婴幼儿期(A组)、学龄前期(B组)、学龄期(C组)3个年龄段常见呼吸道病毒抗体(RV-Ab)、肺炎支原体抗体(MP-Ab)及混合细菌感染(CRP)的阳性率。结果儿童3个年龄段组间大叶性肺炎MP-Ab阳性率、RV-Ab阳性率比较,差异均有统计学意义(P<0.05),且婴幼儿期与学龄前期比较、婴幼儿期与学龄期比较,差异均有统计学意义(P<0.05)。3个年龄段组间常见RV-Ab阳性合并CRP阳性、MP-Ab阳性合并CRP阳性比较,差异有统计学意义(P<0.05);常见RV-Ab阳性合并CRP阳性在学龄前期与学龄期比较,差异有统计学意义(P<0.05);MP-Ab阳性合并CRP阳性比较,在婴幼儿期与学龄期比较,差异有统计学意义(P<0.05)。结论近2年儿童社区获得性大叶性肺炎中婴幼儿以病毒感染为主,学龄前期和学龄期以支原体感染或混合感染为主。

Objective To explore pathogens succession of community-acquired lobar pneumonia in the past two years so as to provide strategy for clinical treatment and precaution.Methods The positive rate of C-reactive protein（CRP）,Common respiratory virus antibody（RV-Ab）,Mycoplasma pneumoniae antibody（MP-Ab） were detected,and then were analyzed retrospectively from 106 in-patients children diagnosed as lobar pneumonia in our department,who were divided into infant group（A group）,pre-school group（B group） and school age group（C group）.Results There was difference in the positive rate of MP-Ab,RV-Ab among three groups（P〈0.05）,and there was difference between A group,B group and C group（P〈0.05）.There was difference in the positive rate of RV-Ab,CRP and MP-Ab together with CRP among three groups（P〈0.05）,and there was difference in the positive rate of RV-Ab together with CRP between B group and C（P〈0.05）,and in the positive rate of MP-Ab together with CRP between A group and C（P〈0.05）.Conclusion The main pathogen of community acquired lobar pneumonia in infants was virus,while the main pathogen in preschool and school age was mycoplasma and/or mixed infection in the last two years.