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卵磷胆固醇脂酰基转移酶与动脉粥样硬化关系的研究进展 被引量:2

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摘要 人体内胆固醇除提供正常生理需要(构成细胞膜、合成类固醇类激素等)外,体内外周组织中多余的胆固醇需要通过血浆高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)运送回肝脏并进一步代谢,这一过程称为胆固醇逆转运(reverse cholesterol transport,RCT)。
作者 潘健源 徐岩
出处 《安徽医学》 2011年第5期689-691,共3页 Anhui Medical Journal
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  • 1ArcaM ,,MontaliA,OmbresD ,etal.LackofassociationofthecommonTaqIBpolymorphisminthecholesterylestertransferproteingenewithangiographicallyassessedcoronaryatherosclerosis[].Clinical Genetics.2001
  • 2UkkolaO,SavolainenMJ,SalmelaPI ,etal.DNApolymorphismsatthelocusforhumancholesterylestertransferprotein(CETP)areassociatedwithmacro andmicroangiopathyinnon insulin dependentdiabetes[].Clinical Genetics.1994
  • 3KuivenhovenJA,JukemaJW,ZwindermanAH ,etal.Theroleofacommonvariantofthecholesterylestertransferproteingeneintheprogressionofcoronaryatherosclerosis[].NewEnglJMed.1998
  • 4GudnasonV,ThormarK,HumphriesSE.InteractionofthecholesterylestertransferproteinI405Vpolymorphismwithalcoholconsumptioninsmokingandnon smokinghealthymen,andtheeffectonplasmaHDLcholesterolandapoA1concentration[].Clinical Genetics.1997
  • 5MitchellRJ,EarlL,WilliamsJ ,etal.PolymorphismsofthegenecodingforthecholesterylestertransferproteinandplasmalipidlevelsinItalianandGreekmigrantstoAustralia[].Human Biology.1994
  • 6Inazu A,Koizumi J,Mabuchi H.Cholesteryl ester transfer protein and atherosclerosis[].Current Opinion in Lipidology.2000
  • 7Rothblat GH,de la Llera-Moya M,Atger V,et al.Cell cholesterol efflux: integration of old and new observations provides new insights[].Journal of Lipid Research.1999
  • 8Kuivenhoven JA,de Knijff P,Boer JM,et al.Heterogeneity at the CETP gene locus.Influence on plasma CETP concentrations and HDL cholesterol levels[].Arteriosclerosis and Thrombosis.1997
  • 9Hill SA,McQueen MJ.Reverse cholesterol transport-a review of the process and its clinical implications[].Clinical Biochemistry.1997
  • 10Ordovas JM,Cupples LA,Corella D,et al.Association of cholesteryl ester transfer protein TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk:the framingham study[].Arteriosclerosis and Thrombosis.2000

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  • 1康爱君,田枫,张阔,周淑佩,郑振辉.载脂蛋白E基因缺陷(C57BL/6J-ApoE)小鼠血脂及病理组织学观察[J].中国比较医学杂志,2006,16(2):85-88. 被引量:12
  • 2李艳,张玉东.高密度脂蛋白胆固醇与冠心病[J].中国心血管病研究,2007,5(11):864-866. 被引量:19
  • 3Trigatti BL, Rigotti A, Braun A. Cellular and physiological roles of SR-BI a lipoprotein receptor which mediates selective lipid up take [J] .Bioehim Biophys Act a,2000,1529(1-3):276-286.
  • 4Xun Chela ,Charlotte Burton, Xuelei Song, et al .An apoA-I mimetic peptide increases LCAT activity in mice through increasing HDL concentration [J]. International Journal of Biological Sciences, 2009,5(5):489-499.
  • 5Julia Save ,Marianne LMitte ,Yann Pueheu ,et al.VeryJow levels of HDL cholesterol and atherosclemsis, a variable relationship □ a review of LCAT deficiency [J]. Vascular Health and Risk Management,2012,6 (8):357-361.
  • 6Berard AM, Foger B, Rein a ley A, e t a.High plasma HDL concenffations associated with enhanced atherosclerosis in transgenic mice over expressing lecithin cholestery lacy-transferase [J]. Nat Med,1997,3(7): 744-749.
  • 7Tanigaw a H, B iUhe ira er JT, Tohyama J, eta. Lecithin cholestero lacyl transferase expression has minimal effects on macrophage reverse cholesterol transport in vlvo [J]. C irculation,2009,120(2): 160-169.
  • 8Dobi 6 soy 6 M,Frohlieh J.Understanding the mechanism of LCAT reaction may help to explain the high predictive value of LDL/HDL cholesterol ratio[J].Physiol Res,1998,47:387-397.
  • 9Dullaart RP,Perton F,Sluiter W J,et al.Plasma lecithin: cholesterol acyl transferase activity is elevated in metabolic syndrome and is an independent marker of increased carotid artery intima media thickness [ J ].J Clin Endocrinol Metab,2008,93:4860-4866.
  • 10Ayyobiaf, Mcgladderysh, Charts, et al. Lecithin cholesterol Acyl transferase (LCAT) deficiency and risk of vascular disease 25 year follow-up [ J ].Atherosclerosis, 2004,177 (2) :361-366.

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