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抗HIV黏膜免疫评价方法研究进展

Research progress in assessment of mucosal immunity to HIV
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摘要 黏膜是人类免疫缺陷病毒(human immunodenciency virus,HIV)侵入机体最主要的途径之一,评价黏膜免疫应答对评价HIV疫苗效果至关重要。用于检测不同动物模型和人体黏膜免疫应答的方法不尽相同,包括黏膜取样方法、样品保存、黏膜标记物种类和检测等方面,因此,建立统一的抗HIV黏膜免疫应答评价系统具有重要的意义。 Mueosa is one of the most main transmission routes of HIV, and it is quite important to assess mucosal immune response for HIV vaccine effect evaluation. The assays for measuring immune response at mucosal sites in various animal models and human, including sampling methods, sample storage, types of mucosal biomarkers and measurements, are different. Thus, to estabilish a consensus set of evaluation system of mucosal response to HIV has important significance.
出处 《国际生物制品学杂志》 CAS 2011年第3期138-142,共5页 International Journal of Biologicals
关键词 HIV 艾滋病疫苗 免疫 黏膜 模型 动物 评价研究 HIV AIDS vaccines Immunity,mucosal Models,animal Evaluation studies
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