球磨机中无溶剂高效合成1,1'-联二萘酚

Solvent-free synthesis of 1,1′-bi-2-naphthanol by ball milling

球磨机中机械力化学作用下,β-萘酚经CuCl2·2H2O氧化偶联,无溶剂固态直接合成1,1'-联二萘酚,产率达91%。最佳反应条件为:球磨机转速350 r/min,n(CuCl2·2H2O)∶n(β-萘酚)=2∶1,研磨时间2 h。同时考察了其他Cu(Ⅱ)/Fe(Ⅲ)的金属盐氧化剂作用的β-萘酚的氧化偶联。

1 ,1＇-Bi-2-naphthanol is prepared with yield of 91% by the coupling of β-naphthol under solvent-free condition in ball mill using CuC12 -2H20 as an oxidant. The optimum conditions are given as follows：l： 12 of the ratio of CuCl2 .2H20 and fl-naphthol by molar and 350 r/min of the rotational speed of the ball mill for 2 hours. The effect of other oxidants of Cu（Ⅱ ）/Fe（Ⅲ） on the coupling of β-naphthol is investigated as well. The chemical structure of the product is characterized by IR and I H-NMR.