蛋白质组学技术在宫颈癌研究中的应用进展

Advances in the application of proteomics in cervical carcinoma research

蛋白质组学技术已广泛应用于肿瘤的发生机制、肿瘤特异性标志物的筛选和鉴定、疗效评价等方面的研究,也应用于宫颈癌的早期诊断、临床分期、筛选治疗靶点等方面的探索,从蛋白质组水平揭示了宫颈癌蛋白质表达谱的变化,为宫颈癌诊断和治疗的发展提供了可靠的理论依据。

Proteomic technology has been widely used in the research of medical sciences,including the study of the pathogenesis of carcinoma,identification of novel biomarkers and evaluating the response to treatment,as well as in early diagnosis,pathologic stages classification and screening therapeutic targets in cervical carcinoma.In the aspect of cervical carcinoma,many reports have demonstrated the differently expressed proteins from the proteome level,and these results provide reliable theoretic base for well understanding of the diagnosis and treatment in cervical carcinoma.