早期乳腺癌前哨淋巴结活检替代腋窝清扫的临床应用

Clinical Practice of Sentinel Lymph Node Biopsy Substituting Axillary Lymph Node Dissection in Early Breast Cancer Treatment

目的:探讨腋窝前哨淋巴结活检术在早期乳腺癌中替代腋窝淋巴清扫术的意义。方法:选择15例早期(T1-2N0M0)乳腺癌患者,用1%亚甲蓝溶液行腋窝前哨淋巴结活检,淋巴结阴性,不行腋窝清扫。结果:15例患者随访1～3年,术后无一例出现患侧上肢肿胀、患侧上肢感觉麻木、运动障碍等并发症。所有患者未发现有局部复发及腋窝肿大淋巴结。结论:对于早期乳腺癌患者,腋窝前哨淋巴结活检阴性可替代腋窝清扫术。

Objective：To study the significance of sentinel node biopsy substituting axillary lymph node dissection in early breast cancer treatment. Methods：Using 1% methylthioninium chloride solution to perform sentinel node biopsy on 15 cases early（T1-2N0M0）breast cancer.The axillary lymph node dissection will not be performed when the biopsy result is negative. Results：In the follow-up examination after 1-3 years,none of the 15 cases suffers from sick side upper limb swelling,numbness or movement disorder.Local recurrence or swelling axillary lymph node is not found in any of the cases. Conclusions：Sentinel lymph node biopsy can be used to substitute axillary lymph node dissection in early breast cancer treatment.