单根毛囊改良分离法在疤痕性秃发毛囊移植中的临床研究

Clinical research of improved single hair follicle isolation in scarring alopecia hair transplant

目的采用改良的单根毛囊分离法得到单根完整毛囊,用于毛发移植治疗头部及眉部的疤痕性秃发,探讨该法应用于疤痕植发的技术要点和临床效果,为毛发移植治疗提供一定的临床数据。方法头部和眉部疤痕性秃发17例患者,使用改良法获得单根毛囊并植入疤痕秃发区域。统计供区所得完整单根毛囊数和受区毛囊成活数,并在术中取所得毛囊进行组织学检查。结果 17例患者随访3～12个月,生长外观自然,原有疤痕基本遮盖。供区毛囊提取率为54.87%～86.01%,受区毛囊成活率为70.27%～96.36%,组织学检查显示毛囊生发结构完整。结论改良分离法获取的单根完整毛囊具生长活性,植入后天获得性的疤痕秃发区域内后生长良好,可改善疤痕区外观。

Objective Applying improved method to isolate and collect the complete single hair follicles,for hair transplant in hair deficiency in head or eyebrow scar.Investigate the main point and effectiveness of this new method.Methods 17 cases of hair deficiency in head or eyebrow scar were treated with hair transplant,applying the new method to isolate and collect the single hair follicles from donor area and then transplant into the scar area.The number of complete hair follicles acquired from donor area and the survival transplanted follicle in recipient area was counted,and histological examination was carried out for the follicle acquired in donor area.Results 17 cases were followed up for 3-12 months,scar areas were almost covered and got natural appearance.The follicle extraction percentage was 54.87%-86.01% and the follicle survival rate was 70.27%-96.36%.The hair follicles growth architecture was complete in histological examination.Conclusion The improved method can get live complete single hair follicles,and the single hair follicles can grow well in the scar area and give good appearances.