笼龛式挤压钉对家兔自体腱骨愈合影响的实验研究

Experimental Study on the Effects of Cage-squeezing Screw on Tendon-bone Healing in a Rabbit Model

研究笼龛挤压钉对家兔自体肌腱移植后移植物腱骨愈合的影响。实验以24只新西兰大白兔为研究对象,将自体髌腱切断后分别以普通挤压钉和笼龛式挤压钉固定于家兔胫骨,分期处死动物。通过大体观察、脱钙、HE染色、甲苯胺蓝染色对移植物止点进行研究。并比较二者的止点的成熟度和止点强度。实验证实笼龛式挤压钉可以显著加速骨隧道的愈合,促进骨壁-交界层-韧带的重塑过程。增强移植物止点的强度。也就是说,笼龛式挤压钉可以明显提高移植物的生物力学性能。

This investigation was to study the effects of cage-squeezing screw on tendon-bone healing in rabbits.The tendons of Twenty four rabbits were severed and fixed with cage-squeezing screw or ordinary squeezing screw on its tibia,and the interface of tendon-bone was tested at the ends of 3,6 and 12 weeks after operations,respectively.The cage-squeezing screw can accelerate bone tunel healing and strengthen the graft intension.The experiments proved that the cagesqueezing screw could help the restructuring process of the graft after the beginning of reconstruction.