超声对冠状动脉粥样硬化与颈动脉粥样硬化的相关性研究

Study on relationship between carotid atherosclerosis and coronary atherosclerosis by ultrasound

目的探讨冠心病患者颈动脉粥样硬化与冠状动脉粥样硬化的相关性。方法对冠状动脉造影确诊为冠心病的89例患者和正常对照组的80例患者行颈动脉超声检查,对比观察颈动脉内-中膜厚度(IMT)、颈动脉有无斑块及斑块类型;对冠心病组不同支病变间IMT、颈动脉斑块积分及斑块发生率进行比较分析。结果①冠心病组患者的颈动脉粥样硬化斑块发生率为87.64%,显著高于对照组(33.75%,P<0.01)。②两组颈动脉斑块以软斑最多见,冠心病组软斑占37.12%,扁平斑占16.59%,混合斑占25.76%,硬斑块占20.53%;对照组软斑占34.09%,扁平斑占22.73%,混合斑占25.00%,硬斑占18.18%。③不同支数冠状动脉病变者之间IMT、颈动脉斑块积分和斑块发生率比较,差异有统计学意义。结论通过超声了解颈动脉病变可间接反映冠状动脉粥样硬化病变的程度。

Objective To explore the relationship between carotid atherosclerosis and coronary atherosclersis in patients with cornary heart disease（CHD）. Methods Eighty - nine patients with CHD confirmed by coronary angiography and 80 eases in normal control group were examined by carotid ultrasound. The carotid intima - media thickness （ IMT）, carotid plaques and plaques types were observed, the IMT, carotid plaque score and plaque incidence in CHD group were analyzed. Results ①The incidence of carotid arteriosclerosis plaques in CHD group was 87.64% , which was higher than that in control group（33.75% ,P 〈0.01 ）. ②The soft plaques were the most common in the two groups. In CHD group, soft plaques occupied 37.12%, flat plaques occupied 16.59%, mixed plaques occupied 25.76% and hard plaques occupied 20.53%, while in control group, soft plaques occupied 34.09% , fiat plaques occuied 22.73% , mixed plaques occupied 25. 00% and hard plaques occupied 18. 18%. ③ There was significant difference of IMT, carotid plaques score and incidence of carotid atherosclerosis plaques in CHD group. Conclusion Ultrasound can indirectly reflect the degree of coronary atherosclersis.