应用MRI对人脑海马三维重建可视化图谱的研究

Reconstruction of three-dimensional atlas of human hippocampus based on the MRI image:a preliminary study

目的应用3.0T MRI特殊扫描构建人类海马三维可视化图谱。方法利用哈尔滨工业大学Bio-X中心开发的软件对3.0T MRI特殊扫描图像的海马边界进行识别、分割等图像转换处理,并进行重建。结果显示双侧海马呈口朝向内上侧"C"形,海马头部较大、尾部缩窄,整体如"逗号"形态。应用透明处理方法进行的三维重建清晰的显示了双侧海马及头、体、尾部三部,甚至肉眼可见的体积及形态差异。结论利用3.0T磁共振特殊扫描可以成功构建人类海马三维可视化图谱。

Objective To establish a 3D atlas of human hippocampus with the 3.0T MRI images.Methods The hippocampus were segmented from the MRI images and reconstructed with the software developed by Haerbin Institute of Technology.Results 3D model of the hippocampus illustrated that they were structure like＂C＂shape whose anterior extremity is enlarged and whose posterior extremity narrows like a comma.The spatial relationship of the head、body、tail can be showed clearly,even if the naked-eye distinctions of volume and morphorlogy.Conclusion It is feasible to establish 3D model of the hippocampus of human brain with the MRI images.