正常犬脊髓MR弥散成像的初步研究

A Preliminary Study on Magnetic Resonance Diffusion Imaging of Normal Canine Spinal Cord

目的探讨正常beagle犬脊髓的磁共振弥散加权成像的可行性、技术特点及研究意义.方法用速眠新对8只比格犬进行麻醉后立即进行脊髓弥散成像,采用西门子sonata1.5T磁共振系统,在平面回波成像(EP)I基础上进行不同参数扫描,分析比较各自影像特点并计算平均表观弥散系数(ADC).结果采用层厚3mm,单次激发SE-EPI弥散序列可以取得较好的颈髓DWI图像,颈髓具有明显的各向异性,平行于白质纤维的弥散梯度可得到较高的ADC值.在颈髓矢状位成像测量的平均ADC值为(109.6±6.8)×10-3 mm2/s.结论 1.5T磁共振系统可以对犬进行颈髓DWI成像,其脊髓成像特点有助于指导犬的脊髓试验.

Objective To explore the feasibility,technical features and research significance of magnetic resonance diffusion-weighted imaging（DWI）of normal canine spinal cord.Methods Eight beagle dogs were anesthetized with Sumianxin,then their spinal cord diffusion imaging was performed immediately.Siemens sonata1.5T MRI System was used to scan with different parameters on the basis of echo-planar imaging（EPI）.The image characteristics was analyzed and compared among these dogs,and their average apparent diffusion coefficient（ADC）was calculated.Results With 3mm of slice thickness,singly stimulated SE-EPI diffusion sequence obtained a better cervical spinal cord DWI.Cervical spinal cord had obvious anisotropy,diffusion gradient parallel to the white matter fiber received a higher ADC value.The average ADC value of the cervical spinal cord sagittal imaging was（109.6±6.8）×10-3 mm2/s.Conclusions 1.5T MRI system can scan magnetic resonance diffusion-weighted imaging（DWI） of canine cervical spinal cord.Exploring the characteristics of the normal canine spinal cord imaging can guide canine spinal cord tests.