期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

儿童慢性乙型肝炎特征及抗病毒治疗 被引量：3

Viral hepatitis B in children:clinical characteristics and antiviral treatment
下载PDF
导出
摘要 在我国儿童中,慢性乙型肝炎是常见病、多发病.儿童时期感染乙型肝炎病毒可致严重临床后果,因此,对有治疗指征患者及时采取合理治疗方案极为重要.而当前国内外对儿童慢性乙型肝炎的治疗尚存诸多问题及争论,如:儿童慢性乙型肝炎患者的治疗指征;选择何种抗病毒药物进行治疗等.为方便广大医师对儿童慢性乙型肝炎做出正确的治疗选择,本文对儿童乙型肝炎病毒感染的自然史、抗病毒治疗指征、抗病毒治疗目标以及抗病毒药物的选择进行系统阐述. Chronic hepatitis B is a common and frequent disease occurring in children in China.Chronic hepatitis B virus infection during childhood may cause serious clinical consequences.Reasonable treatment is extremely important for children with therapeutic indications.However,there are many challenges in the treatment of chronic hepatitis B in children,such as treatment indications and the choice of antiviral therapy.This paper describes the natural history of HBV infection in children,indications for antiviral therapy,goals of antiviral treatment,and choice of antiviral drugs.
作者 赵卫峰 陈良云
机构地区 苏州大学附属第一医院感染科 常熟市第二人民医院传染科
出处 《世界华人消化杂志》 CAS 北大核心 2011年第15期1624-1628,共5页 World Chinese Journal of Digestology
关键词 慢性乙型肝炎 儿童 抗病毒治疗 Chronic hepatitis B Child Antivira treatment
分类号 R725.1 [医药卫生—儿科]
  • 相关文献

参考文献26

  • 1Liang X, Bi S, Yang W, Wang L, Cui G, Cui F, Zhang Y, Liu J, Gong X, Chen Y, Wang F, Zheng H, Wang F, Guo J, Jia Z, Ma J, Wang H, Luo H, Li L, Jin S, Hadler SC, Wang Y. Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination. Vaccine 2009; 27: 6550-6557.
  • 2Hui CK, Leung N, Yuen ST, Zhang HY, Leung KW, Lu L, Cheung SK, Wong WM, Lau GK. Natural history and disease progression in Chinese chronic hepatitis B patients in immune-tolerant phase. Hepatology 2007; 46: 395-401.
  • 3Lok AS, Heathcote EJ, Hoofnagle JH. Management of hepatitis B: 2000--summary of a workshop. Gastroenterology 2001; 120: 1828-1853.
  • 4Chang MH, Hsu HY, Hsu HC, Ni YH, Chen JS, Chen DS. The significance of spontaneous hepatitis B e antigen seroconversion in childhood: with special emphasis on the clearance of hepatitis B e antigen before 3 years of age. Hepatology 1995; 22: 1387-1392.
  • 5Ni YH, Chang MH, Chen PJ, Tsai KS, Hsu HY, Chen HL, Tsuei DJ, Chen DS. Viremia profiles in children with chronic hepatitis B virus infection and spontaneous e antigen seroconversion. Gastroenterology 2007; 132: 2340-2345.
  • 6Boxall EH, Sira J, Standish RA, Davies P, Sleight E, Dhillon AP, Scheuer PJ, Kelly DA. Natural history of hepatitis B in perinatally infected carriers. Arch Dis Child Fetal Neonatal Ed 2004; 89: F456-F460.
  • 7McMahon BJ. The natural history of chronic hepatitis B virus infection. Hepatology 2009; 49: S45-S55.
  • 8ACT-HBV Asia Pacific Steering Committee Members. Chronic hepatitis B: treatment alert. Liver Int 2006; 26: 47-58.
  • 9Chang MH. Natural history and clinical management of chronic hepatitis B virus infection in children. Hepatol Int 2008; 2: 28-36.
  • 10Prati D, Taioli E, Zanella A, Della Torre E, Butelli S, Del Vecchio E, Vianello L, Zanuso F, Mozzi F, Milani S, Conte D, Colombo M, Sirchia G. Updated definitions of healthy ranges for serum alanine aminotransferase levels. Ann Intern Med 2002; 137: 1-10.

同被引文献16

引证文献3

二级引证文献7

世界华人消化杂志
2011年 第15期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部