农村孕妇血总胆固醇水平与围产结局关系分析

Analysis of relationship between maternal total cholesterol level and perinatal outcomes in rural women

目的 分析农村孕妇临产前血总胆固醇水平与围产结局的关系.方法 对170例妊娠28-41周的农村孕妇临产前进行血总胆固醇水平测定,对照分析高总胆固醇组与正常总胆固醇组孕妇子痫前期、妊娠糖尿病、剖宫产、新生儿低出生体重和巨大儿等的发生情况.结果 农村孕妇临产前平均总胆固醇水平为5.56±0.92mmol/L,高总胆固醇53例（31.18%）.高总胆固醇组子痫前期（15.09% vs 4.27%）、剖宫产（30.19% vs 16.24%）及新生儿低出生体重发生率（16.98% vs 3.42%）高于正常总胆固醇组（χ2分别为4.61、4.34、7.68,均P〈0.05）.两组妊娠糖尿病和巨大儿发生率比较无显著性差异（均P〉0.05）.结论 临产前高总胆固醇对围产结局有不利作用.

Objective To analyze the relationship between maternal total cholesterol （TC） level before labor and perinatal outcomes. Methods TC of 170 pregnant rural women was tested before labor. The perinatal outcomes, including preeclampsia, gestational diabetes mellitus （GDM）, cesarean sections （CS）, neonatal low birth weight （LBW） and high birth weight （HBW） were compared between group of high TC level and that of normal range. Results The mean value of TC in rural women was 5.56 ± 0.92 mmol/L, and 53 cases （31.18%） were of high TC. The incidence rate of preeelampsia （ 15.09% vs 4.27% ）, CS （30.19% vs 16.24% ） and LBW （ 16.98% vs 3.42% ） in high TC group was higher than that in normal TC group （X2 = 4.61,4.34,7.68, all P 〈 0.05 ）. There was no significant difference in the prevalence of GDM and HBW between two groups （ P 〉 0.05 ）. Conclusion High maternal TC level before labor has unfavorable effects on perinatal outcomes.