耳石再生机制研究进展

The Progressive Research of Water and Salt Metabolism of Endoly Mphatic and Otolith Regeneration

内耳是一个及声音,运动,和重力的感觉系统,是由一系列被覆特殊上皮细胞的充满内淋巴液的小腔隙组成,包括耳蜗,前庭迷路,和内淋巴囊。内淋巴液位于蜗管、前庭器官的膜质管道中,主要由水、电解质和有机物组成。内淋巴水盐的代谢可能在维持内淋巴稳态及细胞信号传导和耳石再生中有很重要的作用,而其代谢主要是依靠大量的离子通道及特殊蛋白来完成的。本文将简要介绍一些内淋巴的有机质和无机盐,以及其与耳石再生相关性的研究进展。

The inner ear is the sensory system for sound, motion, and gravity. It comprises an array of interconnected fluid compartments that are enclosed by a multitude of specialized epithelial cell, including the cochlea, vestibular labyrinth, and endolymphatic sac. The endolymph lies in membranaceous pipeline of the cochlear duct and vestibular organs, which is mainly composed of water, electrolytes and organic. Endolymphatic might play an important part in the maintenance of water- salt metabolism in lymphoid homeostasis, cell signal transduction and the otolith regeneration, while to complete it, its metabolism mainly relies on a large number of ion channels and special proteins. This article will briefly introduce some important channels associated with water - salt metabolism of endolymphatic, as well as its correlation with otolith regeneration research.