摘要
目的 探讨功能性消化不良与胃排空的关系及普瑞博思的治疗作用。方法 观察普瑞博思对 ６８ 例功能性消化不良患者的治疗作用。胃排空时间测定采用放射学技术检测法。结果 普瑞博思治疗疗程结束时，显效率５６５％ ，有效率 ３０４％ ，总有效率 ８６９％ 。液体胃排空时间治疗前后分别为（４０１±９６）ｍ ｉｎ 和（３８７±８９）ｍ ｉｎ，差异无显著性（ Ｐ ＞ ００５）；固体胃排空时间治疗前后分别为（１２０３±２０１０）ｍ ｉｎ 和（９０５±１８０８）ｍ ｉｎ，差异有显著性（ Ｐ＜ ００１）。结论 普瑞博思可明显加快胃排空，对功能性消化不良有显著的治疗作用。
Objective To study the relationship betw een functional dyspepsia ( F D) and gastric em ptying,and also the therapeutic effect of cisapride on F D. Methods Gastric em ptying tim e for fluid or foods w asm easured by radiologic technique including electrogastrography. The therapeutic effect of cisapride w asclinically observed in 68 F D patients . Results At the end oftherapeutic trial, the pronounced response ratew as 56.5% , the effective rate w as 30.4% , and the overall effective rate w as 86.9% . Pretreatm ent andpost treatm ent gastric em ptying tim es for fluid w ere (40.1±9.6) and (38.7± 8.9) m in, respectively ( P> 0.05) ; but those for solid foods w ere (120.3± 20.1) and (90.5±16.8) m in,respectively ( P < 0.01). Conclusion Cisapride is able to accelerate gastric em ptying offoods, and has obvious therapeutic effect on F D.
