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干扰素治疗病毒性心肌炎的疗效分析 被引量:1

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摘要 目的探讨及研究干扰素治疗80例病毒性心肌炎的临床疗效。方法将我院2008年2月至2010年6月收入院的80例病毒性心肌炎患者随机分成2组,治疗组和对照组各40例。对照组给予复方丹参、维生素C、黄芪等常规药物治疗,治疗组给予常规药物治疗的基础上加用(5~10)万U/(kg·d)的干扰素进行治疗。结果对照组治愈13例,有效12例,无效14例,恶化1例,总有效率为62.5%。治疗组治愈21例,有效16例,无效2例,恶化1例,总有效率为92.5%,治疗组的总有效率为92.5%。结论干扰素副作用小、治疗效果佳,值得临床进一步推广。
作者 李胜林
出处 《中外医疗》 2011年第15期145-145,共1页 China & Foreign Medical Treatment
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  • 1Kyu BS,Matsumori A,Sato Y,et al.Cardiac presistence of cardioviral RNA detected by polymerase chain reaction in a murine model of dilated cardiomyopathy[J].Circulation,1992,86(2):522-530.
  • 2Matsumori A,Wang H, Abelmann WH,et al.Treatment of viral myocarditis with ribavirin in an animal preparation[J].Circulation,1985,71:834-839.
  • 3Fohlman J,Pauksen K,Hyypia T,et al.Antiviral treatment with WIN54954 reduces mortality in murine coxsackievirus B3 myocarditis[J].Circulation,1996,94(9):2254-2259.
  • 4Brinkmann V,Pinschewer D,Feng L.FTY720 suppresses immune response by modulating G-protein coupled receptors on lymphocytes resulting in altered lymphocyte homing[J].Transplantation,1999,(suppl2):S226.
  • 5Yanagawa Y,Masubuchi Y,Chiba K.FTY720,a novel immunosuppressant,induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats,Ⅲ.Increase in frequency of CD62L-positive T cells in Peyer′s patches by FTY720-induced lymphocyte homing[J].Immunology,1998,95:591-594.
  • 6Luo ZJ,Tanaka T,Kimura F,et al.Analysis of the mode of action of a novel immunosuppressant FTY720 in mice[J].Immunopharmacology,1999,41:199-207.
  • 7Chiba K,Yanagawa Y,Masubuchi Y,et al.FTY720,a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats.I.FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing[J].J Immunol,1998,160:5037-5044.
  • 8Miyamoto T,Matsumori A, Hwang M W,et al.Therapeutic effects of FTY720,a new immunosuppressive agent,in a murine model of acute viral myocarditis[J].J Am Coll Cardiol,2001,37(6):1713-1718.
  • 9Ahoot J,Galindo A, Alejos JC,et al.USE of OKT3 for acute myocarditis in infants and children[J].J Heart Lung Transplant,2000,19:1118-1121.
  • 10Kishimoto C,Takada H,Kawamata H,et al.Immunoglobulin treatment prevents congestive heart failure in murine encephalomyocarditis niral myocarditis associated with reduction of inflammatory cytokines[J].J Pharmacol Exp Ther,2001,299(2):645-651.

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